10 Best CBD Oil Reviews 2021: Buying Guide & Effectiveness

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

Royal CBD Oil

Royal CBD

  • Full-spectrum and offer an array of benefits.
  • The hemp that they extract their oils from is American-grown with sustainable farming practices.
  • They have a wide variety of CBD products like tinctures, CBD topicals, and edibles.



  • The brand creates all-organic and non-GMO CBD products.
  • The CBD products are full-spectrum with no traces of THC.
  • CBDistillery offers synergy blends most brands lack.

Spruce CBD

  • The hemp that they source the CBD oil from is American-grown.
  • Third-party tested.
  • They offer the best CBD oils for pain.

CBD has indeed been demonstrated to have various health advantages[1] that could aid some maladies and medical disorders. They include pain, anxiety, sleeping[2] issues, and arthritis[3].

CBD is available in various forms, including capsules, gummies, and creams, but oil tinctures are the most popular. A graduated dropper is included with the best CBD oils to help you correctly measure your consumption. Continue reading to learn more about the top 10 best CBD oil brands on the market that provide top-notch CBD oils.

Best CBD Oils on the market in (December. 2021)

  • Royal CBD – Editor’s choice
  • CBDistillery – Best CBD oils for anxiety.
  • Spruce CBD – Best with high potencies.
  • CBDfx – Best for sleep.
  • CBDPure – Best natural formula
  • Joy Organics – Best organic
  • Nuleaf Naturals – Best full-spectrum for pain.
  • Lazarus Naturals – Most reasonably priced.
  • CBD Essence – Best for mobility, anxiety, and pain
  • Hemp Bombs – Best premium products

What Is CBD Oil?

CBD oil is one of many cannabinoids found in the hemp plant. CBD oil comes in three types: full-spectrum, broad-spectrum, and CBD isolate. Full-spectrum oils contain natural compounds found in the hemp plant, including a little trace amount of THC. These types tend to have high potencies.

Then the broad-spectrum CBD oils and the CBD isolates do not have THC. But broad-spectrum has secondary cannabinoids like terpenes and flavonoids.

Using CBD oils is pretty elementary as the instructions on using them are usually indicated on the container. You can use CBD oils as an ingestible tincture. You simply place a few drops under or on the tongue. Some CBD brands also produce CBD topicals where you mix the concentrated oil with a carrier oil like olive oil or coconut oil and apply it directly to the skin.

The Line Up At A Glance

Royal CBD Oil

Editor’s choice

Royal CBD

  • Full-spectrum and offer an array of benefits.
  • The hemp that they extract their oils from is American-grown with sustainable farming practices.
  • They have a wide variety of CBD products like tinctures, CBD topicals, and edibles.


Best for anxiety.


  • The brand creates all-organic and non-GMO CBD products.
  • The CBD products are full-spectrum with no traces of THC.
  • CBDistillery offers synergy blends most brands lack.


Best with high potencies.

Spruce CBD

  • The hemp that they source the CBD oil from is American-grown.
  • Third-party tested.
  • They offer the best CBD oils for pain

cbdfx tincture

Best for sleep.


  • CBDfx combines its oil with carrier oils like coconut oil to boost absorption.
  • You can get targeted formulas to aid sleep, relaxation, health, and wellness, among others.
  • Some of their oils contain extra cannabinoids like CBG and CBN.


Best natural formula


  • The CBD oils are sourced from organic American-grown hemp.
  • Third-party tested.
  • The CBD products in this brand are affordable.

Joy Organics CBD Oil

Best organic

Joy Organics

  • They offer a wide range of broad and full-spectrum CBD oil tinctures.
  • The brand has a great reputation in the industry.
  • They offer customization to their dosages.

Nuleaf Naturals

Best full-spectrum for pain.

Nuleaf Naturals

  • They offer full-spectrum CBD products with high potency.
  • The CBD oil source is American-grown hemp with no contaminants.
  • The company’s CBD products are third-party tested.

Lazarus Natural

Most reasonably priced.

Lazarus Naturals

  • All Lazarus Naturals CBD products are third-party tested.
  • The company formulates high-quality CBD products.
  • Lazarus Naturals retails premium CBD isolate products.

CBD Essence

Best for mobility, anxiety, and pain

CBD Essence

  • CBD Essence is a reputable CBD oils brand.
  • All CBD Essence oils are third-party tested.
  • The company offers an attractive 60-day money-back guarantee.

Hemp Bombs

Best premium products

Hemp Bombs

  • The product line-up in this brand is extensive.
  • The CBD products are top-shelf and have great tastes and flavors
  • Hemp Bomb’s CBD products are all third-party tested.

Benefits of Best CBD Oil

CBD oils proffer many benefits to the human body; below are the most appreciated:

It Elevates Pain

The endocannabinoid system[4] (ECS) is specialized in the human body for regulating several processes such as sleep, appetite, pain, and immune system response. Endocannabinoids are neurotransmitters produced by the body that connect to cannabinoid receptors in the central nervous system.

CBD has been demonstrated to alleviate chronic pain[5] by influencing endocannabinoid receptor function, decreasing inflammation, and interacting with neurotransmitters.

A combination of CBD and THC has been demonstrated to help relieve pain associated with multiple sclerosis[6] and arthritis[7] in several human studies.

It Helps Cure Anxiety and Depression

Anxiety, stress, tension, and depression are prevalent psychological conditions that can have severe consequences for one’s health and wellbeing. CBD oil has shown potential as a therapy for psychological distress, piquing the curiosity of many people who suffer from these conditions.

In one Brazilian trial[8], 57 males were given either edible CBD or a placebo 90 minutes before being put through a mock public speaking assessment. According to the scientists, a 300-mg dose of CBD was the most efficient at considerably calming the mind during the experiment.

The placebo, a 150-mg CBD dose, and a 600-mg CBD dose did not affect anxiety.

Yet another commendable benefit of CBD oil linked to healing depression is that CBD oil can treat insomnia and anxiety in youngsters[9] who have been diagnosed with post-traumatic stress disorder. CBD’s ability to operate on serotonin receptors[10] in the brain, a neurotransmitter that governs mood and social behavior, is connected to these properties.

It Can Help Eradicate Acne

Acne is a common skin condition that arises when there is an imbalance in the production of sebum. Genetic makeup, germs, subsurface irritation, and the glut of sebum in the skin are all factors that contribute to acne.

According to recent scientific studies, CBD oil is an effective treatment for acne due to its anti-inflammatory qualities and capacity to lower sebum production.

CBD oil suppressed sebaceous gland cells from secreting excess sebum. It also has anti-inflammatory effects[11] and blocks the stimulation of pro-acne chemicals such as inflammatory cytokines.

CBD is Purported to Have Neuroprotective Properties

CBD’s usage in treating neurological illnesses such as epilepsy and multiple sclerosis is the most researched area. Several studies have shown encouraging outcomes, even though research in this area is still relatively new.

Sativex, a CBD-and-THC-based oral spray, is a safe and effective treatment for muscle spasticity[12] in persons with multiple sclerosis.

Sativex reduced spasms in 75% of 276 persons with multiple sclerosis who had medication-resistant muscle spasticity.

But that is not all!

More research has found that CBD medication improves the health of a person with Parkinson’s disease and wellbeing, plus better sleeping patterns[13].

CBD has also been found in more animal and test-tube tests to reduce swelling and averts the neurodegeneration linked with Alzheimer’s disease[14].

CBD was given to rats genetically susceptible to Alzheimer’s disease in one long-term trial, and it was found to help minimize cognitive deterioration.

CBD is a Potent Fighter Against Cancer

CBD may help inhibit the progression[15] of certain forms of cancer, according to a survey. Cancer cells appear to have suppressed development and get destroyed by the chemical.

CBD has a low toxicity[16] threshold. However, more research into how CBD could help standard cancer treatments is needed.

It could be added to chemotherapy medications to boost the immune[17] system’s response to cancer treatment.

CBD is a Possible Treatment of Type 1 Diabetes

Type 1 diabetes develops when the body’s immune system destroys the pancreatic cells, resulting in swelling.

Researchers discovered evidence in 2016[18] that CBD may help reduce inflammation and prevent or slow the progression of 1 diabetes.CBD proved to have neuroprotective effects on diabetic rats in a 2018 study[19], notably memory preservation and nerve inflammation reduction.

10 Best CBD Oils Reviews

Royal CBD

Royal CBD Oil

Royal CBD has focused on customer satisfaction for many years and made itself one of America’s favorite brands. They have satisfied customers coming back for more because there are so many benefits from using it.

  • Full-spectrum CBD products provide an entourage effect to customers.
  • Sustainable hemp extract farming procedures are used to produce the product.
  • 30-day money-back guarantee.
  • Royal CBD is on the more expensive side of CBD products

Royal CBD uses American-grown hemp to produce its products that come from organically grown seeds. They don’t use any artificial flavors or sweeteners, so you can enjoy pure pharmaceutical-grade cannabis without the need for added chemicals.

They’re also committed to helping those suffering from chronic pain, depression, and anxiety. It is achievable through a safe product distribution service that provides only quality OGs at affordable prices.

Thanks to this innovative new way forward while being environmentally responsible through reduced carbon footprint reduction techniques, Royal CBD is making significant strides in the industry.



CBDistillery’s CBD products are available in a variety of forms to suit your needs. They have various CBD oils, topical creams, gels, and tinctures for those who prefer taking their medication this way.

If you need some help with arthritis sy

  • The United States Hemp Authority has issued them certifications.
  • They provide an excellent selection of CBD Oils for numerous benefits.
  • CBDistillery sustainably grows hemp plants.
  • Their website is not user-friendly.
  • Their CBD products are not available for international shipment.

CBDistillery is a Colorado-based company that strives to bring affordable and high-quality CBD. They offer potent CBD extracts in all certifications, including FDA approval for pet-friendly tinctures. You can also get an Indica dominant strain when you need soothing relief from your worries, no matter the state of your mind.

When it comes down to deciding on just the right kind of CBD oil, you can count on this brand. For instance, a person with epilepsy who doesn’t want anything too strong to knock them out entirely or some elderly patients don’t like marijuana smell.

Spruce CBD


Spruce is a company that has been producing high-strength CBD oil for years. Their Super Strength Hemp Oil contains 80 mg of cannabinoids per milliliter and can relieve symptoms like inflammation, neuropathic discomfort, or radiculopathy[20] to make your day more comfortable.

You will also boost your mood, immunity[21] enhancement, and many more benefits.

  • All of Spruce CBD’s products are certified organic. 
  • All CBD products are non-GMO and free of additives.
  • They have Full-spectrum CBD oils for arthritis and joint pain.
  • All of their goods have undergone extensive third-party testing.
  • They only sell a small number of CBD products.
  • They only ship within the United States.
  • They only come in two strengths.
  • The oils are pricey.

Spruce CBD is a family-friendly North Carolina brand that focuses on organic, third-party lab-tested products. They have been around for a while and are backed by people who care about your wellness.

Their full-spectrum oil contains no pesticides or herbicides, so it’s safe to use even if you’re pregnant or younger than 18 years old. Many customers love how well this product works – many of them say they feel less pain after taking Spruces’ C02 Hemp Oil, and they get to enjoy the entourage effect[22].


cbdfx tincture

The CBDfx wellness tinctures contain a powerful cannabinoid called CBG[23] that’s used to ease the pain. They also have coenzymeQ10[24] and curcumin, which are natural anti-inflammatory compounds available in four strengths:

  • It has a special recipe that helps to reduce inflammation.
  • All of the company’s goods have undergone extensive third-party testing.
  • In their lineup, they have four potencies.
  • They don’t have formulas that cover the entire spectrum.
  • CBDfx doesn’t have a lot of taste selections.

With CBDfx, you can find a wide range of products for every need. From pets and children to topical treatments or diuretics. Something here will suit your individual needs, whether it’s for pain relief or inflammation.

Additionally, they offer two natural anti-inflammatory compounds, coenzymeQ10 and curcumin, making it easier than ever before to get all the benefits without any side effects.



CBDPure offers a wide range of high-quality CBD products. With 3rd party lab results from independent laboratories all over North America and an incredible 90-day money-back guarantee on their hemp extract products.

The 60ml sizes come in 300mg strength, 600mg, or 1000 mg options for those looking to sample different strengths at one time as well.

  • They offer full-spectrum CBD oil that is high in cannabinoids, which aid in pain alleviation.
  • All of the company’s CBD products have undergone extensive third-party testing.
  • They have unflavored natural mixtures available.
  • 90-day money-back guarantee.
  • Their website is lacking information about the company and its products.
  • They feature a large selection of CBD oils with low potency.

One of the most trusted suppliers for full-spectrum CBD oil, capsules, and creams in Washington state is CBDPure. The company has been around since 2016 with a simple yet effective lineup that provides customers what they need to feel their best: quality products sourced directly from organic hemp farms in the USA.

As shown by third-party lab reports confirming high cannabinoid content, including minor cannabinoids such as CBC/CBDV, this makes an even more beneficial effect for an arthritis patient who wants relief without any side effects or complications.

Joy Organics

Joy Organics CBD Oil

The joy of cannabis is here for everyone! Joy Organics offers four different potencies to meet your needs.

  • Its formula is THC-free and its products are the best organic CBD oil.
  • The brand comes in four different potencies and tastes.
  • All of their items have compliant certificates of testing and quality assurance.
  • They offer a wide range of CBD products with a broad spectrum of effects.
  • They don’t have any high-potency alternatives.
  • Minor cannabinoids are present in tiny amounts in their products.

Joy Organics is a brand that specializes in CBD isolates. They offer only organic Colorado-grown hemp, and their products have been tested for potency by third-party labs to make it easy on consumers who want assurance about what they are using.

The CBD oil tinctures can be enjoyed alone or mixed into drinks. The topical oils and creams provide natural protection against sun damage on your skin. At the same time, edibles allow you to enjoy the benefits without feeling worried after using them once too many times.

Nuleaf Naturals

Nuleaf Naturals

The company has built its reputation on providing high-quality full spectrum tinctures that are among some of the best around when it comes to pain relief, making them an easy choice when you’re searching through all those options out there.

  • Nuleaf produces the highest-quality full-spectrum solution for pain relief.
  • They have a stellar reputation and brand recognition all over the world.
  • They provide free delivery.
  • All of their CBD products have undergone extensive third-party testing.
  • The company’s CBD products don’t come in a wide range of flavors.
  • There is only one potency of CBD product available.

NuLeaf Naturals is a leader in the CBD industry, and they’re known for their commitment to quality. In 2014 NuLeAF started selling only full-spectrum oils highlighting how much work goes into producing the CBD product type above what’s required by law or even good business practice when it comes down to your final product (not including flavor).

Since then, we’ve seen them perfecting the process using organically grown cannabis extract from Colorado’s top farms resulting in no artificial flavors added during production.

Lazarus Naturals

Lazarus Natural

Lazarus Naturals is committed to making sure that its products are both healthy and safe. They avoid using any artificial preservatives, gluten, or animal byproducts in the production process.

  • The brand is a member of several important national and business organizations in the hemp industry.
  • Veterans, persons with impairments, and members of low-income households receive a 60 percent discount on all their products.
  • They provide unique CBD products.
  • They do not ship worldwide
  • Some clients do not like the way the CBD oil tinctures taste.

Founded by Sequoia Price-Lazarus in 2014, the company is renowned for its transparency concerning the source and production of its products. It all began when he met one of his friend’s mothers who had cancer but needed CBD to relieve her discomfort.

Chronically ill people are forced into poverty due to high-priced medicine which made him realize how money should not stand between anyone seeking help if there’s a chance of affordable solutions. That is why Lazarus Naturals have the best prices.

CBD Essence

CBD Essence

Customers praise its potency by saying it provides fast relief without any side effects, and the best part is you can use this oil in several different ways for a wide range of symptoms.

  • Their products are all-natural and organic.
  • To assure the finest quality as they manufacture small batches in limited amounts.
  • They offer a money-back guarantee of 60 days.
  • Their formula is liposomal.
  • Every refund must be approved.
  • The majority of the information provided by the advertiser is not available.

CBD Essence is committed to purity and quality, so they grow their hemp organically in the Florida sun. Their products are made with only 100% natural ingredients. For example, premium Full Spectrum CBD Extracts come from carefully selected strains grown without pesticides or herbicides. This is vital for increased medicinal benefits while also being safe on your system overall.

The company takes pride in offering an extensive selection that includes capsules & tinctures, and CBD topical creams!

Hemp Bombs

Hemp Bombs

The Hemp Bombs company does not just want you to live a pain-free life—they also care about your quality of living. The best part is that their CBD oils work and help alleviate joint discomfort in patients who have not found relief from other treatments like prescription medication or surgery.

  • They offer a diverse range of products.
  • All of the CBD in Hemp Bombs is organic.
  • The CBD products from Hemp Bombs have a delicious flavor.
  • The CBD products are a little on the pricey side.
  • They have CBD isolate items available.

Hemp Bombs is a Tampa, Florida-based company that produces all-natural CBD products. They have strict quality control measures to ensure their customers are getting only what’s best for them. They ensure that the CBD products do not have any harmful pesticides or herbicides.

Hemp bombs also do vertical operations of extraction at their purest form through packaging by hand. This ensures you’re receiving high-end isolates instead of Full Spectrum Extracts being sold elsewhere where there could potentially still be trace amounts from other sources outside the product’s desired specifications.

How To Choose The Best CBD Oil for Sale?

When it boils down to what is the best CBD oil on the market, these are a few things you should consider:

The Price Best Quality CBD Oil

The number one thing that most people look at when gauging CBD brands to go with is pricing. Indeed, some CBD brands are a bit more costly than others, but the point of reference should be the quality of the CBD extracts versus the price.

Is the full-spectrum CBD oil they have on their line-up as potent as they propose? Or does the mg of the CBD oils enough to take you through a month?

These are some of the questions you need to ask yourselves. To find this out, be vigilant to check out any CBD oil reviews, studies, and client remarks on social media, review sites, and even word of mouth.

The Potency of the CBD Product

Potency is essential as it tells you the strength of the CBD   product. Potency is also vital as it dictates the dosage you need to take. Different usages that you have will dictate the potency you need. When you are using pure CBD for arthritis pain, or relaxation, the dosages will differ.

For instance, an example of potencies is 700 mg, 1000 mg, etc.

What Type of CBD Oil

This implies which kind of CBD oil provides the effect you want. These include full-spectrum, broad-spectrum, and CBD isolate. Even though they are all effective, they are made of different components.

Full-spectrum includes all cannabinoids found from the cannabis plant, including terpenes, CBG, CBN, flavonoids, and small traces of THC. Taking this will proffer you the entourage effects of all the other components of the hemp plant.

Broad-spectrum CBD oil contains all the cannabinoids but has zero THC, and Isolates have none of the other Cannabinoids but CBD only.

The type you choose will depend on why you are taking CBD oil. And the best person to guide you through the best kind is your physician or CBD expert who knows the best CBD oils for you.

CBD Oil Dosage?

When it comes to dosage, it depends on the potency and why you need CBD oil. Dosage is usually measured in mg, and the brand usually indicates the number of mg their oils have.

Again, the dosage will differ according to the reason you are taking it. For instance, a daily dose of approximately 40 mg of CBD might do the trick to get rid of joint pain. And taking pure CBD oil for sleep will be at 25mg. All in all, the final word should come from a physician specializing in your condition.

Potential Side Effects of CBD Oil

Because CBD is still a relatively new point of research, there is still a lot that scientists know about it. And the most significant area is its side effects. CBD oils are usually well-tolerated with minimal results, but they can still proffer you the following mild side effects[25]:

  • Dry mouth.
  • Diarrhea.
  • Reduced or elevated appetite.
  • Drowsiness.
  • Fatigue.
  • Risky interactions with other medications like blood thinners.

The Bottom Line 

Because everyone’s body reacts to CBD oil differently, there is no one-size-fits-all solution. To find a mix that works for you, you may need to experiment with different products, CBD spectrums, and CBD forms. This list of the top 10 CBD oils for sale might assist you in deciding which one to try.

Frequently Asked Questions

What are the Benefits of CBD Oil?

CBD oil has been researched for its possible involvement in reducing the symptoms of various common health problems, including anxiety, depression, acne, and heart disease. It may potentially provide a healthy remedy for pain and other symptoms treatment for cancer patients.

What are the disadvantages of CBD oil?

CBD can induce unfavorable effects like fatigue, dry mouth, decreased appetite, diarrhea, and tiredness even though it’s usually well taken. Other medications you’re taking, like blood thinners, may interact with CBD. Another source of alarm is the inconsistency of CBD quality and dosage in goods that you must verify.

Is it safe to consume CBD oil daily?

Not only can you, but you should take CBD regularly for the best results in most circumstances.

Is CBD going to show up on a drug test?

CBD will not show up in a drug test because it is not screened for in drug tests. However, because CBD products may include THC, you may fail a drug test after using them.

Do you keep CBD oil in the fridge?

To avoid additional exposure to air, keep CBD oil in its original package. Store oil at room temperature, usually between 60 and 70 degrees Fahrenheit (16 and 21 degrees Celsius). Keep the oil in the dark, out-of-the-way spot, such as a pantry, cabinet, or closet.

Medically reviewed by:

Mitchelle Morgan is a health and wellness writer with over 10 years of experience. She holds a Master's in Communication. Her mission is to provide readers with information that helps them live a better lifestyle. All her work is backed by scientific evidence to ensure readers get valuable and actionable content.

Medically reviewed by: